Tramadol is an opioid analgesic sold under the brand name Ultram. It is commonly used to treat and manage moderate to severe pain when all other non-opioid pain medications fail to work or are ineffective on the pain. 

This medication is recommended and FDA-approved for use only on a doctor’s prescription for short-term pain treatment, as it complies with its safe-to-use regulation. 

Being an opioid analgesic (a medicine used to relieve pain), it has a higher potential for abuse and misuse, and taking it regularly for a prolonged period can develop a dependency that leads to addiction over time. 

Those who are suffering from any moderate to severe pain can safely use this medication on a doctor’s prescription to get instant relief from pain. 

How Does Tramadol Work?

Tramadol directly affects the opioid receptors in the central nervous system of the brain. It reduces the feeling of pain by interrupting the way nerves signal pain between the brain and the body and changing the way the body responds to pain.

Dosing Information 

Extended-release tablets take about 12 to 14 hours to release the formula and dissolve it in the body to relieve pain. 

For Acute Pain – 

• The initial recommended dose of this medication for adults is 50 mg—100 mg, taken every 4 to 6 hours. The dose should not exceed 400 mg a day. 

For Chronic Non-Cancerous Pain –

• The initial recommended dose for people 18 years or older is 100 mg, taken orally once a day. After 5 days, the dose may be increased to 150, 200, or 250 mg. The maximum daily dosage is 300 mg.

Tramadol is not recommended for pediatric patients and to treat cancer pain. People who do not use immediate-release tablets can use extended-release tablets on a doctor’s prescription after evaluating their risks and benefits. 

Side Effects Of Tramadol 

Tramadol causes mild to severe side effects that can sometimes be life-threatening to a person. Some of the most common and notable side effects of Tramadol are as follows.

Common Side Effects Of Tramadol 

• Headache
• Sleepiness or tiredness
• Nausea and vomiting
• Dizziness 
• Stomach pain
• Itching

Serious Side Effects Of Tramadol

Some of the most serious side effects of Tramadol are described below –

Severe Allergic Reactions—Tramadol may cause certain allergic reactions. Get immediate medical help if you experience any symptoms of allergic reactions.

Breathing Problems—Tramadol may cause slow or shallow breathing, especially if you already have breathing problems caused by other conditions or take other medications that affect breathing. 

Serotonin syndrome – If you have too much serotonin in your body, using Tramadol and other medicines that affect serotonin can cause serotonin syndrome. 

Seizures – The use of Tramadol has been reported to cause seizures sometimes. Seizures are of many different types and are not easy to recognize. 

Suicidal thoughts – In some cases, if not used according to a doctor’s prescription, it can cause thoughts of suicide. 

Reduced Adrenal Functions—Using Tramadol in the long term can cause your body’s adrenal glands to stop making cortisol (the stress hormone), known as adrenal insufficiency. This condition can get worse if your body is under stress due to fever, surgery, or trauma.

Low Blood Pressure: Tramadol may lower your blood pressure. Contact a doctor immediately if you experience fainting, dizziness, or an urge to lie down. 

Low-Blood Sugar Level – Using Tramadol can cause low blood sugar, which can be dangerous and may cause death. 

Severe Skin Reactions – Contact a doctor if you experience itching, rashes, swelling, or hives on your skin.

Who Should Not Use Tramadol?

Avoid using Tramadol if you have any of these health conditions, such as –

• Children younger than 12 years of age
• Allergic reaction 
• A condition that causes seizures or fits
• Kidney or liver problem 
• Head injury
• Response to other strong painkillers
• Addiction to alcohol or recreational drugs
• Breastfeeding, fertility, or pregnancy

What Should I Know Before Using It?

To prevent any severe side effects, withdrawal symptoms, and drug interaction that can be fatal to your health, you must know these things before using Tramadol for safe and effective use.

• Talk to your doctor if you are a habitual drinker or if you have any substance use disorder before using this medication to prevent any adverse effects that can be harmful to your health.

• Pregnant women should avoid using this medication to prevent premature birth of the baby. 

• Avoid overdosing or increasing the dose, as it can lead to respiratory depression. 

• Please do not use this medication regularly, more often, or for a prolonged period to avoid dependency and addiction to it. 

• Tell your doctor, and avoid using Tramadol if you have multiple health issues or severe liver disease. 

• Avoid using Tramadol if you have liver or kidney problems or if you are 65 years or older. 

• Do not take any other opioid medication while using Tramadol. Otherwise, it can lead to severe drug interactions that may prove to be fatal to your health. 

• Children below 12 should not use this medication without consulting a doctor. 

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